Biological network analysis (Fall 2008) [236632] – Network Biology is an emerging research field which aims to decipher complex cellular processes by modeling them as networks of interactions between various molecules. The course will review state-of-the-art algorithms and computational methods in the field along with their applications to the study of real network data. A special focus will be given to an exceptional modeling approach for metabolic networks, called constraint-based modeling, which relies on optimization theory and has various interesting bioengineering and biomedical applications. Other topics will cover structural analysis of protein-protein interaction and regulatory networks via graph theoretic and statistical methods with an emphasis on biological applications.