MetaPathwayHunter
 

MetaPathwayHunter is a pathway alignment tool that, given a query pathway and a collection of pathways, finds and reports all approximate occurrences of the query in the collection, ranked by similarity and statistical significance. It is based on a novel, efficient graph matching algorithm that extends the functionality of known techniques.

The program also supports a visualization interface with which the alignment of two homologous pathways can be graphically displayed.

 

 

 

Windows OS:

  • You can download the beta version from here.

  • Version 1.1 can be downloaded from here.

Linux OS:

  • Version 1.1 can be downloaded from here.

MAC OS:

  • Version 1.1 can be downloaded from here.

 

 

A description of the algorithm with some details on how to set parameters and the use of the tool can be obtained as:

         

  R. Y. Pinter, O. Rokhlenko, E. Yeger-Lotem, M. Ziv-Ukelson: "Alignment of Metabolic Pathways"; Bioinformatics, Vol. 21, No. 16  (August 2005), pp. 3401-3408.