Israel Steinfeld (israels AT cs technion ac il)

I'm currently a PhD student in the field of Computational Biology, at the Computer Science department in the Technion, under the supervision of Dr. Zohar Yakhini

Fields of interest

Analysis and design of high-throughput measurement technologies.

System biology.

The effect of chromatin structure on gene expression regulation.

Academic Degrees

B.Sc. - Bioinformatics, Cum Laude, Tel Aviv University, 2000-2004

M.Sc. – Life Science, Summa Cum Laude, Tel Aviv University, 2004-2007

Thesis: The Influence of Chromatin Modifiers on Transcription.

Advisors: Prof. Ron Shamir and Prof. Martin Kupiec

Past Projects

GOrilla

Multi Knowledge

SIMBA

EXPANDER

MonoClad

UnMeRFi

Teachings

TA in the course “Introduction to C language”, Spring 2009, Winter 2010

TA in the course "Laboratory for bioinformatics tools”, Spring 2004-2005 (TAU)

TA in the course "General Genetics", Fall 2004-2005 (TAU)

Publications

Navon R, Wang H, Steinfeld I, Tsalenko A, Ben-Dor A, Yakhini Z.

Novel rank-based statistical methods reveal microRNAs with differential expression in multiple cancer types.

PLoS One. 2009 Nov 25;4(11):e8003

Straussman R, Nejman D, Roberts D, Steinfeld I, Blum B, Benvenisty N, Simon I, Yakhini Z, Cedar H.

Developmental programming of CpG island methylation profiles in the Human genome.

Nat Struct Mol Biol. 2009 May;16(5):564-71. Epub 2009 Apr 19.

Eden E, Navon R, Steinfeld I, Lipson D, Yakhini Z.

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists.

BMC Bioinformatics. 2009 Feb 3;10(1):48.

de Smith AJ, Walters RG, Coin LJ, Steinfeld I, Yakhini Z, Sladek R, Froguel P, Blakemore AI.

Small deletion variants have stable breakpoints commonly associated with alu elements.

PLoS ONE. 2008 Aug 29;3(8):e3104.

Steinfeld I, Navon R, Ardigò D, Zavaroni I, Yakhini Z

Clinically driven semi-supervised class discovery in gene expression data.

Bioinformatics. 2008 Aug 15;24(16):i90-7.

Perry GH, Ben-Dor A, Tsalenko A, Sampas N, Rodriguez-Revenga L, Tran CW, Scheffer A, Steinfeld I, Tsang P, Yamada NA, Park HS, Kim JI, Seo JS, Yakhini Z, Laderman S, Bruhn L, Lee C

The fine-scale and complex architecture of human copy-number variation.

Am J Hum Genet. 2008 Mar;82(3):685-95. Epub 2008 Jan 24.

Steinfeld I, Shamir R and Kupiec M

A genome-wide analysis in Saccharomyces cerevisiae demonstrates the influence of chromatin modifiers on transcription.

Nat Genet. 2007 Mar;39(3):303-9.

Tanay A, Steinfeld I, Kupiec M and Shamir R

Integrative analysis of genome-wide experiments in the context of a large high-throughput data compendium.

Mol Syst Biol. 2005;1:2005.0002. Epub 2005 Mar 29.

Shamir R, Maron-Katz A, Tanay A, Linhart C, Steinfeld I, Sharan R, Shiloh Y, Elkon R

EXPANDER - an integrative program suite for microarray data analysis.

BMC Bioinformatics. 2005 Sep 21;6:232.

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