Abstract:

The rapid accumulation of cellular data (e.g. sequencing of
genes and genomes and measurements of gene expression, protein
interactions and ribosome densities) enables developing computational
models of biological processes to address fundamental biomedical
questions.
In this talk I will survey our recent results in portraying molecular
evolution and in understanding and predicting gene translation.
Specifically, I will describe: (1) a new approach for inferring ancestral
genomic sequences based on co-evolutionary relations; and (2) a novel
computational analysis of the dynamic ribosome movement, a key to
understanding gene translation.

The talk is self-contained and requires no prior knowledge in Biology.